Reproduction Abstracts

Introduction: A sucessful implantation depends on the exquisite coordination between embryo and maternal uterus. N-myc downregulated gene 2 (NDRG2) belongs to the NDRG gene family, a new class of Myc-repressed genes, and possesses tumor suppression function. Given the similarities between embryo implantation and the growth of cancer cell, the present study was undertaken to examine the expression and regulation of NDRG2 during peri-implantation period.Ma...

Introduction: Immune tolerance at the feto–maternal interface must be established during the processes of implantation and pregnancy. Monoclonal nonspecific suppressor factor beta (MNSFβ) is a secreted protein that possesses antigen-nonspecific immune suppressive function. The objective of this study was to establish the MNSFβ gene knockout mouse model, observe and analyze its reproductive phenotypes to further explore the roles of MNSFβ played in mouse emb...