Reproduction Abstracts

Introduction: The ovarian follicle has a three-dimensional structure in which the oocyte is surrounded by tightly connected follicle cells that mediate the action of external signals and nourish the gamete during its maturation. In vitro follicle techniques provide a tool to model follicle development in order to investigate basic biology and are further being developed as a technique to preserve human fertility or to product transgenic animals for cell therapies. Mai...

Introduction: Androgens: testosterone, dihydrotestosterone (DHT), and a fungicide with antiandrogenic activity – vinclozolin (Vnz) served to study agonism and antagonism of the androgen receptor.Material and methods: Granulosa cells (GC) isolated from pig follicles were cultured for 48 h with testosterone (10−7 M), DHT (10−7 M), and Vnz (1.4×10−5 M) separately or in combinations. Cells were the...