Reproduction Abstracts

The purpose of this study is the effects of growth differentiation factor 8 (GDF8) and SB431542 (SB) on porcine oocytes in vitro maturation (IVM), subsequent embryonic development after in vitrofertilization (IVF). We were investigated the effect of GDF8 and SB treatment during IVM on nuclear maturation, intracellular glutathione (GSH), reactive oxygen species (ROS) levels, analyzed specific gene transcription and translation levels in cumulus cells after IVM, and emb...

Transgenic (TG) pigs are currently regarded as an important animal model for various biomedical researches including a disease modeling and a regenerative medicine. We tried to develop a pig astrocyte-specific CreERT2-LoxP recombination system as a part of TG pig model of brain tumor arisen from astrocytic cell lineage. We designed two vector systems one retains pig glial fibrillary acidic protein (GFAP) promoter-CreERT2 transgene and the other has GFP ge...