Reproduction Abstracts

Brain mechanism responsible for LH surge generation shows sexual dimorphism in rodents. The dimorphism is considered to be due to the perinatal estrogen converted from testicular androgen during developing period. The present paper aimed to clarify the mechanisms mediating the estrogen-induced defeminization of LH surge-generating system. The microarray analysis is an attempt to obtain the candidate gene(s) mediating the perinatal estrogen action causing the brain sexual diffe...