Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p298 | (1) | WCRB2014

Decidual stromal cell regulation of trophoblast in first trimester pregnancies with normal and impaired spiral artery remodelling

James-Allan Laura , Wallace Alison E , Whitley Guy S , Cartwright Judith

Introduction: Decidualisation of the endometrium is the differentiation of uterine stromal cells into specialised secretory decidual stromal cells (DSC) primed for pregnancy. If pregnancy occurs, DSC control and regulate fetal trophoblast invasion. Pre-eclampsia is a disorder associated with inadequate trophoblast invasion and spiral artery (SA) remodelling. Uterine artery Doppler resistance index (RI) in the first trimester of pregnancy measures the extent of SA remodelling; ...