ra0001p237 | (1) | WCRB2014
Kamalyan Lilit
, Vijayan Vijith
, Brauns Ann-Kristin
, Colasante Claudia
, Schuler Gerhard
, Luers Georg H
, Baumgart-Vogt Eveline
Introduction: Peroxisomes are ubiquitous organelles, which play an essential role in human physiology. Besides other metabolic pathways, peroxisomes are involved in β-oxidation of fatty acids, ROS-metabolism, and cholesterol synthesis, wherefore alterations of peroxisomal metabolism might affect steroid metabolism and the regulation of corresponding signaling pathways. Indeed male patients with peroxisomal dysfunction exhibit either cryptorchidism or a range of testicular...