ra0002p029 | (1) | SRF2015
Rose Belinda Vivienne
, Cabrera-Sharp Victoria
, Cameron Ian
, Crabtree James
, Crowhurst James
, Firth Marvin
, Ghosh Sharmila
, McGladdery Andrew
, Neal Huw
, Pynn Jan
, Pynn Oliver
, Raudsepp Terje
, Smith Charlie
, Verheyen Kristien
, Wathes D Claire
, Wise Zara
, de Mestre Amanda
Early pregnancy loss (EPL) in the mare is defined as loss of pregnancy between initial detection and day 65 of gestation. It occurs in 710% of pregnancies and yet little is known about the underlying pathologies. A lack of suitable conceptus material has limited investigation into the role of chromosomal defects in EPL. The objective of this study was to develop a method to isolate and culture placental cells isolated from failed pregnancies to enable further genetic cha...