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ra0002p010 | (1) | SRF2015

Characterisation of the dog as a sentinel species for human exposure to endocrine disrupting chemicals

Sumner Rebecca , Byers Andrew , Taylor Oliver , Moxon Rachel , White Natasha , Craigon Jim , Zhang Zulin L , England¹ Gary C W , Lea Richard

Introduction: A temporal decline in canine male fertility parallels that reported in the human. Our hypothesis is that this is associated with exposure to environmental chemicals (ECs). We investigated i) a relationship between canine testicular chemical profiles and Sertoli cell numbers and ii) the effects of testicular concentrations of chemicals on sperm DNA fragmentation, motility and vitality.Methods: Canine adult testes (routine castrations) from t...

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Characterisation of the dog as a sentinel species for human exposure to endocrine disrupting chemicals

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