ra0003p009 | (1) | SRF2016
Plenagl Susanne
, Busse Mandy
, Nowak Desiree
, Schumacher Anne
, Zenclussen Ana Claudia
Introduction: During pregnancy, the maternal immune system has to tolerate the semi-allogenic fetus while protecting the mother and the unborn against pathogens. Subclinical infections that danger the fetus constitute a challenge for the medical system. A useful model to study mechanisms underlying infection-driven fetal death is a LPS-based mouse model. The recognition of LPS, a component of gram-negative bacteria membrane, leads to an immune answer that takes place through T...