Reproduction Abstracts

Introduction: Selective progesterone receptor modulators (SPRMs) have been reported to decrease cell proliferation within uterine fibroids, and reduce menstrual blood loss. The SPRM Ulipristal Acetate (UPA) has an anti-proliferative effect on fibroid tissue, yet its impact on endometrial cell proliferation is not well understood. The aim of this study was to quantify the effects of the SPRM UPA administration on endometrial cell proliferation within the human endometrium.<...