Reproduction Abstracts

Introduction: Toll-like receptors (TLRs) are active molecules expressed on the surface of ovarian cancer (OC) cells, but the consequences of TLR2/TLR4 signaling pathways in these cells remain unclear. Because melatonin (mel) act as an immunomodulatory hormone and has been reported to modulate TLRs in some aggressive tumor cells, we investigated the effective role of long-term mel therapy on TLR2- and TLR4-mediated molecule myeloid differentiation factor 88 (MyD88)-dependent si...