ra0002p053 | (1) | SRF2015
Standing Andrew
, Georgiou Christiana
, Bano Gul
, Mason Helen Diane
, Rice Suman
In recent years it has become apparent that vitamin D3 (VD) has a fundamental role in reproductive function, with deficiency of the hormone being implicated in several reproductive pathologies: endometriosis, pre-eclampsia and PCOS. VD is essential for oestrogen synthesis in both males and females; via indirect mechanisms of calcium homeostasis but also direct regulation of aromatase expression. Women with PCOS are more likely to suffer from VD deficiency, with an inverse corr...