Reproduction Abstracts

The evolutionarily conserved Wnt/β-catenin signal transduction pathway controls many biological processes. The objective of this study was to determine the role of this signaling pathway in follicular development and luteal function. To this purpose PMSG–eCG gonadotropin-prepubertal treated female rats were injected with a Wnt inhibitor (XAV939, 5 μg/ovary, Wnt-I group) or vehicle (DMSO, control group) into the bursa of both ovaries the day of hCG administration...