Reproduction Abstracts

Introduction: The poly(ADP-ribosyl)ation (PARylation) has involvement with pro-survival autophagy. However, there has been no report about PARylation and autophagy during pre-implantation development. Here, we investigated the mechanism between PARylation and pro-survival autophagy in pre-implantation development.Materials and methods: IVF embryos were cultured in the medium containing 3-aminobenzamide (3ABA), parp inhibitor. Autophagy and PARylation wer...