Reproduction Abstracts

Introduction: Several subsets of uterine natural killer lymphocytes (uNK cells) home to early decidua basalis in rodents and humans. UNK cells peak at midgestion when uNK cells synthesizing the angiokines placenta growth factor (PGF), vascular endothelial growth factor (VEGF) and Delta-like ligand 1 (DLL1) are dominant. UNK cell-driven angiogenesis regulates the timing of both uterine lumen closure and early, post-implantation conceptus development. UNK cells contribute to ort...