Reproduction Abstracts

Implantation failure remains a bottleneck in assisted reproduction treatments (ARTs), as only ~25% of treatment cycles result in a live birth. During the early stages of implantation, endocrine and embryonic paracrine signals prime the receptivity of the uterine luminal epithelium (LE) before the trophectoderm (TE) of the blastocyst-stage embryo can mediate attachment and subsequently invade the uterine epithelium and stroma. We have developed an in vitro model using ...