Reproduction Abstracts

Introduction: The production of recombinant protein in transgenic domestic animal is one of the major successes of biotechnology. Knock-in system is a more powerful method to produce mammary gland bioreactor. This study is conducted to development of knock-in somatic cells using bovine β-casein genome for produce of biological substance.Material and methods: The knock-in vector was constructed by using 5.9 kb fragment of upstream of bovine β-ca...