Reproduction Abstracts

Lysophosphatidic acid (LPA) is a bioactive lipid mediator that exerts a wide range of biological actions. LPA acting specifically through LPA receptor 1 (LPAR1) seems to be essential for the development of fibrosis in several organs. We determined whether the LPA–LPARs signalling system correlates to equine endometrial fibrosis (endometrosis). A total of 24 uteri from diestrus (n=6 for each category: I, II A, II B, and III according to Kenney and Doig classificat...