Reproduction Abstracts

Introduction: G9A-like protein (GLP) plays an important role in early mouse embryonic development as GLP-deficient embryos display severe growth retardation and defects, leading to lethality around embryonic day 9.5. In this study, we investigated the early role of GLP in controlling cell fate decisions by employing siRNA, which depleted both maternal and embryonic GLP mRNA during the mouse pre-implantation embryo. Our study demonstrates that GLP def...