Reproduction Abstracts

In our previous study, we demonstrated that pigs expressing neonatally lethal phenotype induced by genetic modification could be rescued by induction of chimerism by using blastocyst complementation. Here, we show that the obtained chimeric pigs can faithfully transmit the genotype, which is the cause of the lethal traits, to progenies.Cloned embryos (male) of pigs showing the phenotype of pancreatogenesis deficiency by expression of the Pdx1-Hes1</e...