Reproduction Abstracts

Human parturition at term and preterm involves inflammatory and non-inflammatory pathways and includes activation of the intrauterine prostaglandin (PG) cascade, resulting in synchronised membrane rupture, cervical dilation, and myometrial contractility. A key mediator of uterine PG production is the highly inducible enzyme cyclooxygenase 2 (COX2 or PTGS2). We have identified steroid receptor coactivator interacting protein (SIP or KANK2) to be highly expressed in human myomet...