Reproduction Abstracts

Mammalian gonads arise in both sexes from bilateral urogenital ridges that have the potential to develop as ovaries or testes. In mice, the genital ridges are first evident at embryonic day (E) 9.5. At E10.5, a critical switch in gonad development occurs in which XY gonads express the testis-determining gene (sex-determining region Y chromosome) Sry. Sry belongs to the SOX family of nuclear transcription factors. Male...