ra0003o016 | SRF Student Prize Session | SRF2016
Siemienowicz Katarzyna
, Coukan Flavien
, Lerner Avigdor
, Franks Stephen
, Rae Mick
, Duncan Colin
Women with Polycystic Ovary Syndrome are at increased risk of developing insulin resistance, obesity and dyslipidemia. Amplified metabolic perturbations during puberty may be a central factor contributing to metabolic phenotype of adult PCOS. Using a clinically realistic ovine model of PCOS we reported hyperinsulinaemia and early fatty liver changes, with no difference in body weight and adiposity, in adolescence.Here we aimed to further examine metaboli...