ra0003p018 | (1) | SRF2016
Hwang Seon-Ung
, Yoon Junchul David
, Han Yongquan
, Eun Kiyoung
, Kim Hyunggee
, Hyun Sang-Hwan
Transgenic (TG) pigs are currently regarded as an important animal model for various biomedical researches including a disease modeling and a regenerative medicine. We tried to develop a pig astrocyte-specific CreERT2-LoxP recombination system as a part of TG pig model of brain tumor arisen from astrocytic cell lineage. We designed two vector systems one retains pig glial fibrillary acidic protein (GFAP) promoter-CreERT2 transgene and the other has GFP ge...