Reproduction Abstracts

Context: In mammalian female germ cells, meiotic entry occurs during fetal life. The current model places retinoic acid (RA) as a key signal inducing meiotic initiation by activating the expression of stimulated by retinoic acid 8 (Stra8), a necessary factor for pre-meiotic chromosomal replication. However, the requirement of RA for meiotic initiation has been recently questioned in the female germ cells.Material and method: To clarify whether R...