ra0001p016 | Ovary | WCRB2014
Duan Xing
, Wang Zhen-Bo
, Cui Xiang-Shun
, Kim Nam-Hyung
, Sun Shao-Chen
Introduction: ROCK (Rho kinase) is a Rho-GTPase effector that is involved in various cellular functions, such as stress fiber formation, cell migration, tumor cell invasion, and cell motility. In this study, we investigated possible roles for ROCK in mouse oocyte meiosis and embryo development.Materials and methods: Time lapse microscopy, immunofluorescence staining, western blotting, RNAi and inhibitor treatment were adopted to analyze the roles of ROCK...