Reproduction Abstracts

The oocyte influences hormonal and cellular changes in the follicle and the ovary. Theca cells, surrounding the follicle basement membrane, synthesise androgen and thus regulate ovarian oestrogen production. The vascular theca layer provides nutrients to the avascular inner follicle. In C1galt1 mutant mice, all oocytes lack core 1-derived O-glycans due to oocyte-specific ablation of core 1 beta 1,3-galactosyltransferase. C1galt1 mutants have increase...