Reproduction Abstracts

Introduction: Studies in primates indicated that AMH promotes preantral follicle growth, but inhibits antral follicle estradiol (E2) production in vitro. Thus, experiments were designed to investigate the role of AMH on primate follicular development in vivo during the spontaneous menstrual cycle.Materials and methods: Hemi-ovariectomized, adult rhesus macaques (n=5) first received vehicle (control) treatment by intraovarian infusion from cycle ...

Introduction: Recent studies indicate that dietary habits and hyperandrogenemia influence ovarian function in women. However, data are limited regarding the effects of western-style diet (WSD) and androgen (e.g. T) on follicle development, especially during the early follicular stage, in primates. The current study investigated the impact of WSD alone and with chronic T exposure on gene expression in small antral follicles (SAFs) of macaques.Materials an...