ra0001s019 | SRD Plenary Lecture | WCRB2014
Tsukamura Hiroko
Kisspeptin-GPR54 signaling plays a key role to govern reproductive function through regulating GnRH/gonadotropin release in mammals, including rodents, ruminants, reflex ovulators, and primates. Surge and pulse modes of GnRH/gonadotropin secretion are responsible for ovulation and gametogenesis/steroidogenesis, respectively. It has been suggested that kisspeptin neurons located in the anterior hypothalamus, such as the anteroventral periventricular nucleus (AVPV) and preoptic ...